A study finds many Vietnam veterans may have contracted liver flukes decades ago that could now cause pancreatitis, liver disease and/or bile duct cancer.
The Department of Veterans Affairs commissioned a study that looked at bile duct cancer and liver flukes that may have been ingested by veterans while on tour in Southeast Asia during the Vietnam War.
This was in response to a story reported by the Associated Press in which 700 cases, of cholangiocarcinoma, bile duct cancer, were seen in VA facilities over the last 15 years.
The current small study looked at 50 blood samples, finding 20% of which to be positive for liver flukes. Most participants were not aware they were infected. If infection did later lead to cancer, symptoms would come late in the diagnosis.
Tropical medicine specialist, Sung-Tae Hong, from Seoul National University in South Korea, stated he was “surprised” by the results and admits to more research needing to be done.
Cholangiocarcinoma is still rare, however if Vietnam veterans are at increased risk due to their fish consumption while on duty, they need to be followed closely by their medical provider. Stool tests could be done to look for parasite eggs, and blood tests may look for antibodies fighting the infection.
Liver flukes are parasites that infect the liver and bile duct. There are multiple species. The disease Fasciola hepatica and Fasciola gigantica cause is called fascioliasis. Symptoms may range from none to severe liver disease. But the liver flukes associated with bile duct cancer include Opisthorchis viverrini, O. felineus, and Clonorchis sinensis. According to the US Department of Veterans Affairs:
The irritation and scarring caused by liver fluke infection can lead to bile duct cancer.
Two parasites are commonly involved. One is Opisthorchis verrini, which is found in Southeast Asian countries, including Thailand, Lao People’s Democratic Republic, Vietnam, and Cambodia. The other is Clonorchis sinensis, which is common in rural areas of Korea and China.
Eating raw or undercooked fish infected with these parasites introduces the pathogen into the GI system where it can hide out in the liver and bile ducts for decades.
In 2007, Sripa et al discussed how close to 600 million people were at risk of being infected with liver flukes.
In 2011, Lim et al wrote, “More than 35 million people worldwide are infected. The exceptionally high incidence of cholangiocarcinoma in Thailand and Korea is attributed to the high prevalence of liver fluke infection in these areas.”
In addition to ingesting undercooked contaminated fish, liver flukes can infect multiple mammals, such that eating infected cattle or sheep liver (if undercooked) could transmit the parasite. Ingesting vegetables washed with contaminated water could introduce the fluke into a person as well.
Medical News Today recommends boiling all untreated water and to avoid water from a stream near where cattle and sheep live.
Although some people with liver flukes may exhibit no symptoms at all, some may incur:
Jaundice – yellowing of the skin and whites of eyes
According to cancer.net, the 5 year survival, meaning living 5 years past diagnosis, is 30%, assuming the cancer stays locally. If the cancer spreads to regional lymph nodes prognosis for 5 year survival drops to 24%. Distant spread of the cancer reduces the 5 year survival rate to 2%.
Anti-Parasitic medications, such as triclabendazole, have proven effective against Fasciola. Praziquantel has been effective in fighting Opisthorchis infections.
You just know that any business wants to reduce its tax burden as much as it can. Without doubt, Apple has a huge number of accountants at its beck and call to find ways to reduce its corporate income tax bills by billions of dollars.
But Apple’s methods of handling its taxes have been the subject of severe criticism, more so with the release of the so-called Paradise Papers, leaked to a German newspaper, which contain documents purportedly revealing how the rich and the famous manage their offshore cash. Apple was included in the list, but it wasn’t the only company whose finances came into question. Other companies reportedly include Facebook, Twitter, Disney, Uber, Nike, Walmart and even McDonalds.
I mean, it’s a huge list. But with Apple in the crosshairs, the company claimed that the data contained in those papers wasn’t accurate or misleading, that it pays more taxes than any company on the planet, and that it “pays every dollar it owes in every country around the world.”
As the U.S. Congress debates revisions to the country’s complex and confusing tax laws, ways might be sought to convince domestic companies with huge offshore cash hoards to repatriate that money. You also expect Apple to deny that it does anything but obey the law, even if it has to be done creatively. But some corporations pay no tax at all, including GE. So the billions Apple remits might indeed be, as they claim, more than the others.
Which brings us to the fact that, a few weekends ago on The Tech Night Owl LIVE, we featured outspoken commentator and podcaster Kirk McElhearn. The main focus was on taxes, and whether Apple is unfairly reducing its corporate tax burden by strategic parking of its huge offshore money hoard. Apple has selected the small island of Jersey in the Channel Islands, which has ties to the UK. Jersey is also the birthplace of actor Henry Cavill, famous for portraying Superman on the big screen.
In a series of statements, Apple claims that it pays billions of dollars in taxes every year, and that it is complying with the law regardless of the skepticism about such practices, but Kirk doesn’t believe it. The discussion shifted from taxes to electric cars, as Kirk explained that he owns a Toyota Yaris Hybrid. Among the models mentioned is the somewhat pricy BMW i3, and the new compact-sized Tesla, the Model 3, which is still confronting problems in ramping up production.
You also heard from prolific author Bob “Dr. Mac” LeVitus, who talked about the ongoing fear-mongering from some members of the media about the iPhone X and its Face ID and other features. Bob explained that, despite the advertised backorder situation, he was able to buy one from his mobile carrier and receive it on the day it was released. But will he keep it? He appeared to be skeptical of its perceived advantages, but will make a decision while he still has time to return it for a refund. He said he is also holding off publishing a review while he considers its value. Bob also discussed the use of iPads in major league baseball, and how it may have helped the Houston Astros win the World Series. He also said that you shouldn’t be in a rush to install a new OS on your Mac, iPhone or iPad, and maybe wait a short while to make sure there aren’t any serious bugs that’ll cause you trouble. You can listen to the entire show here.
That same weekend on our other radio show, The Paracast: Gene and Chris present MUFON Executive Director Jan C. Harzan. He discussed the state of UFO research, and what the organization has learned in its 48 years of existence; it was founded in 1969 as the Midwest UFO Network. He’ll also discuss concerns about MUFON’s policies and staff shakeups, and about the reasoning behind the controversial 2017 symposium that featured lectures on the alleged U.S. secret space program and some especially outrageous speakers. Harzan is a 37-year veteran at IBM, and holds a B.S. in Nuclear Engineering. He’s been Executive Director of MUFON since 2013. You can listen to the entire show here.
IS APPLE FINALLY GETTING THE LOVE FROM CONSUMER REPORTS?
Consumer Reports magazine claims to be incorruptible because it buys all the products it tests and retail, and won’t allow companies to use its reviews in their advertising. On the surface, it all sounds credible. But I’ve long felt that its test results are often unfairly skewed against Apple. Are corporate politics at play?
Indeed, Apple has had a curious history with CR, and you can decide whether it’s received fair treatment. Consider the iPhone 4, released in 2010. Do you remember AntennaGate? If you held the handset in a certain way, reception quality would nosedive. You could see the signal strength dip precipitously in YouTube videos of the time, and it appeared to be a potential source of trouble.
So Steve Jobs sarcastically remarked that you should hold it differently. That suggestion went over like a lead balloon, so Apple invited the media to a press conference where they actually allowed some of them to tour its multibillion dollar antenna test facility. According to Jobs, other smartphones exhibited similar symptoms when held in certain ways, and Apple posted videos of telling examples, but CR still decided not to recommend the iPhone 4. Other mobile handsets were not similarly downgraded.
Although Jobs claimed the phenomenon was due to the laws of physics, Apple still offered free bumper cases for a time, which certainly eliminated the problem. Next year’s model, the iPhone 4s, in addition to the debut of Siri, sported a redesigned antenna symptom designed to reduce signal loss when you held it the “wrong way.”
The next purported scandal was BendGate. Amid reports that the iPhone 6 Plus might be unduly prone to bending under such conditions as placing it in your back pocket, CR decided to see if Apple did it again. But they didn’t. Tests indicated that its resistance to bending was acceptable and comparable to other mobile gear. But the following year, Apple made moves to strengthen the aluminum case on the iPhone 6s and 6s Plus to make it even more difficult to bend one.
That takes us to the MacBook Pro with Touch Bar. CR has a peculiar method of testing battery life that involves loading some test sites from a server repeatedly with browser caching off. It’s not that people use browsers that way, except for development purposes.
On the Mac, that involved invoking Safari’s Develop menu, again something few people do in the real world, and deactivating caching. This evidently triggered an obscure macOS Sierra bug that caused repeated loading of web icons. So battery life was inconsistent, and CR said it couldn’t recommend the new MacBook Pros.
In turn, Apple realized it had a problem on its hands and reached out to CR. At the end of the day, a minor OS update fixed the problem, and the MacBook Pro achieved extremely high battery rates as a result even if they were, as I said, entirely unrelated to what normal users would achieve. It was, therefore, now recommended.
In passing, you can no longer disable the cache in Safari for macOS High Serra, although the cache can be emptied.
On the day the iPhone X went on sale, CR placed “secret shoppers” in the lines at Apple Stores to buy a dozen of them. They were quickly added to the test queue.
According to CR: “Based on those early impressions, the new iPhone makes good on Apple’s promise of delivering something bigger and better.”
In a very positive early review, the iPhone X survived drop tests that have caused other gear, including some copies of the Samsung Galaxy S8, to self-destruct. The OLED display was found to deliver superior performance, “with deep blacks and accurate colors.”
Face ID? Evidently CR had few problems with it under normal use. For the most part, it worked as advertised, except for extreme situations where someone pulled a baseball cap down to their eyebrows, caught a look at the iPhone X while it was placed beneath a table, or when glancing at it from the side while driving.
Aside from those edge cases, it did seem that Face ID “rarely stumbled.” CR didn’t mention the twin test, where identical or near-identical twins might fool the device. In other words, it was as close to perfect as one might expect for such a product. After all, Touch ID doesn’t work all the time.
The magazine’s preliminary conclusion? “With its starting price of $999, the iPhone X isn’t a purchase to take lightly. But it’s worth mentioning that the costs of high-end components—such as OLED displays and 4K video cameras—are pushing other phones, such as those made by Apple’s rival Samsung, closer to the $1,000 mark, too.”
It’s refreshing to see a reminder that the iPhone X is not the only expensive smartphone out there. The Samsung Galaxy Note 8 costs up to $960, U.S., at some dealers, although there is widespread discounting. On a monthly basis, the price difference between the Note 8 and the iPhone X is may be a dollar or two. Both offer 64GB of storage. True, the iPhone X is much more expensive if you opt for the 256GB model, but Samsung doesn’t offer anything comparable.
But I’m not reading endless blogs that Samsung is gouging its customers by selling gear for only a little less than the iPhone X. Only Apple gets dinged for a pricing decision that probably makes sense to the company’s marketers and bean counters.
Does this mean the iPhone X will be rated above the previous high scorer, Samsung, when the review is complete? In the past, iPhones have scored a tad lower than Samsung’s gear, in part, due to shorter battery life, so I suppose we’ll see.
In the meantime, it’s a promising start, and I’m curious to see where the final rating is set, considering how well it appears to have scored so far. But with CR, there could be a surprise or two that’ll reflect poorly on Apple, or the totals will be weighted questionably to somehow favor Samsung.